High-throughput and label-free enrichment of malignant tumor cells and clusters from pleural and peritoneal effusions using inertial microfluidics-Reference-Cited by-同舟云学术

High-throughput and label-free enrichment of malignant tumor cells and clusters from pleural and peritoneal effusions using inertial microfluidics

Published:2022 Issue:11 Volume:22 Page:2097-2106
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Zhu Zhixian¹,Li Shuang²,Wu Dan³,Ren Hui¹,Ni Chen¹,Wang Cailian²,Xiang Nan¹^ORCID,Ni Zhonghua¹^ORCID

Affiliation:

1. School of Mechanical Engineering, and, Jiangsu Key Laboratory for Design and Manufacture of Micro-Nano Biomedical Instruments, Southeast University, Nanjing, 211189, China

2. Department of Oncology, Zhongda Hospital, Southeast University, Nanjing, 210009, China

3. Department of Oncology, Jiangyin People's Hospital, Jiangyin, 214400, China

Abstract

We developed a polymer microfluidic chip with slanted spiral channels for high-throughput and label-free enrichment of malignant tumor cells and clusters from clinical effusions.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Six Talent Peaks Project in Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D2LC00082B

Reference48 articles.

1. In vitro cell culture of patient derived malignant pleural and peritoneal effusions for personalised drug screening