Synthesis and crystal structure of new monometallic Ni(ii) and Co(ii) complexes with an asymmetrical aroylhydrazone: effects of the complexes on DNA/protein binding property, molecular docking, and in vitro anticancer activity
Author:
Affiliation:
1. School of Chemical Engineering
2. Nanjing Forestry University
3. Nanjing 210037
4. P. R. China
5. Jiangsu Key Lab for the Chemistry & Utilization of Agricultural and Forest Biomass
Abstract
Cytotoxic nickel and cobalt complexes containing asymmetrical aroylhydrazone were synthesized and their interactions with HS–DNA and BSA protein were investigated, which was supported by molecular docking studies.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA10283F
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