N-Hydroxy-Phe-Phe, a new dipeptide, and cytotoxic macrocyclic trichothecenes from the lethal toxic mushroom Podostroma cornu-damae

Author:

Lee Bum Soo1,Jung Su Myung2,Ryoo Rhim3,Choi Sang Un4,An Seongpil5,Kim Ki Hyun1ORCID

Affiliation:

1. School of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea

2. Department of Biological Sciences, Sungkyunkwan University, Suwon 16419, Republic of Korea

3. Special Forest Products Division, Forest Bioresources Department, National Institute of Forest Science, Suwon 16631, Republic of Korea

4. Korea Research Institute of Chemical Technology, Deajeon 34114, Republic of Korea

5. SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University (SKKU), Suwon 16419, Republic of Korea

Abstract

A new dipeptide, N-hydroxy-Phe-Phe (1), and three macrocyclic trichothecenes, namely satratoxin H (2), 12′-episatratoxin H (3), and roridin F (4), were isolated from a plate culture of the poisonous mushroom Podostroma cornu-damae.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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