Photoinduced cytotoxicity of photochromic symmetric diarylethene derivatives: the relation of structure and cytotoxicity

Author:

Nakagawa Yuma1ORCID,Hishida Tatsuya1,Hatano Eri1,Sumaru Kimio2ORCID,Morishita Kana2,Morimoto Masakazu3ORCID,Yokojima Satoshi45ORCID,Nakamura Shinichiro5ORCID,Uchida Kingo15ORCID

Affiliation:

1. Department of Materials Chemistry, Faculty of Science and Technology, Ryukoku University, Seta, Otsu, Shiga 520-2194, Japan

2. Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5th, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan

3. Department of Chemistry and Research Center for Smart Molecules, Rikkyo University, 3-34-1 Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan

4. School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

5. Cluster for Science Technology and Innovation Hub Nakamura Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

Abstract

The photoinduced cytotoxicity of twelve diarylethene derivatives having thiazole or pyridine rings in their molecules was evaluated in terms of molecular structure and size.

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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