Synthesis of chiral R/S-pseudopeptide-based Cu(ii) & Zn(ii) complexes for use in targeted delivery for antitumor therapy: enantiomeric discrimination with CT-DNA and pBR322 DNA hydrolytic cleavage mechanism
Author:
Affiliation:
1. Department of Chemistry
2. Aligarh Muslim University
3. Aligarh 202002
4. India
Abstract
The detailed mechanism of the hydrolytic cleavage pathway of 1S with pBR322 d DNA and the molecular docked model with DNA are shown below.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA24770A
Reference43 articles.
1. Cancer Prevention
2. Ferrocifen type anti cancer drugs
3. The status of platinum anticancer drugs in the clinic and in clinical trials
4. Classical and Non‐Classical Ruthenium‐Based Anticancer Drugs: Towards Targeted Chemotherapy
5. Targeted Chemotherapy with Metal Complexes
Cited by 30 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. De novo design and preparation, structural details, and cytotoxic response of a new water soluble (2,2′–bipy)–(phenylalaninato)–μ–chlorido–copper(II) drug candidate against resistant cancer cells;Journal of Molecular Structure;2024-11
2. De novo design and preparation of Copper(II)–based chemotherapeutic anticancer drug candidates with Boc–glycine and N,N–donor ligands: DNA binding, cleavage profile, and cytotoxic therapeutic response against MCF–7, PC–3, and HCT–116 cells;Polyhedron;2024-09
3. DNA binding, cleavage and anticancer activity of a Zn(II)-Cu(II) hetero-dinuclear carbohydrazone complex containing the secondary ligand 1,10-phenanthroline;Results in Chemistry;2023-12
4. Development of new cobalt, copper, and zinc complexes of Schiff-base ligands as prospective chemotherapeutic agents;Polyhedron;2023-11
5. Molecular interaction of lysozyme with therapeutic drug azithromycin: Effect of sodium dodecyl sulfate on binding profile;International Journal of Biological Macromolecules;2023-07
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3