Dietary l-tryptophan alleviated LPS-induced intestinal barrier injury by regulating tight junctions in a Caco-2 cell monolayer model-Reference-Cited by-同舟云学术

Dietary l-tryptophan alleviated LPS-induced intestinal barrier injury by regulating tight junctions in a Caco-2 cell monolayer model

Published:2019 Issue:5 Volume:10 Page:2390-2398
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Chen Mengdie¹²³⁴⁵^ORCID,Liu Yuyu¹²³⁴⁵,Xiong Shanbai¹²³⁴⁵,Wu Moucheng¹²³⁴,Li Bin¹²³⁴⁵^ORCID,Ruan Zheng⁶⁷⁸⁹⁴,Hu Xiaobo¹²³⁴⁵

Affiliation:

1. College of Food Science and Technology

2. Huazhong Agricultural University

3. Wuhan 430070

4. China

5. Key Laboratory of Environment Correlative Dietology

6. State Key Laboratory of Food Science and Technology

7. School of Food Science and Technology

8. Nanchang University

9. Nanchang 330047

Abstract

The intestinal epithelial layer forms a barrier through cell–cell tight junctions and breaking or even slightly disrupting this barrier can lead to serious pathological consequences, including infection and inflammation.

Funder

Ministry of Education of the People's Republic of China

Agriculture Research System of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/FO/C9FO00123A

Reference44 articles.

1. Intestinal barriers protect against disease

2. Regulation of the epithelial barrier by post-translational modifications of tight junction membrane proteins

3. Architecture of tight junctions and principles of molecular composition

4. Cell–Cell Junctions Organize Structural and Signaling Networks

5. Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1

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