A ratiometric ESIPT probe based on 2-aza-Cope rearrangement for rapid and selective detection of formaldehyde in living cells

Author:

Quan Tingting12,Liang Zhenhao12ORCID,Pang Huaiting12,Zeng Guanling12,Chen Tongsheng123ORCID

Affiliation:

1. MOE Key Laboratory of Laser Life Science & Institute of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, China

2. Guangdong Provincial Key Laboratory of Laser Life Science, College of Biophotonics, South China Normal University, Guangzhou 510631, China

3. SCNU Qingyuan Institute of Science and Technology Innovation Co., Ltd, Qingyuan 511517, China

Abstract

A ratiometric ESIPT probe, FormAFP, has been developed for rapid, selective and sensitive detection of FA via 2-aza-Cope rearrangement. The probe also showed a fast response (<20 min) to both exogenous and endogenous FA in living cells.

Funder

Natural Science Foundation of Guangdong Province

Guangzhou Municipal Science and Technology Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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