Nanoincorporation of curcumin in polymer-glycerosomes and evaluation of their in vitro–in vivo suitability as pulmonary delivery systems

Author:

Manca Maria Letizia12345,Peris José E.6789,Melis Virginia6789,Valenti Donatella12345,Cardia Maria Cristina12345,Lattuada Donatella1011125,Escribano-Ferrer Elvira61314159,Fadda Anna Maria12345,Manconi Maria12345

Affiliation:

1. Department Scienzedella Vita e dell’Ambiente

2. CNBS

3. University of Cagliari

4. Cagliari

5. Italy

6. Department of Pharmacy and Pharmaceutical Technology

7. University of Valencia

8. Valencia 46100

9. Spain

10. Department of Medical Biotechnologies and Translational Medicine

11. University of Milan

12. Milan

13. School of Pharmacy. Institute of Nanoscience and Nanotechnology

14. University of Barcelona

15. Barcelona

Abstract

This work was aimed at deliver curcumin to lungs by its incorporation into innovative vesicles glycerosomes and polymer-glycerosomes, the latter obtained combining glycerosomes with two polymers: sodium hyaluronate and trimethyl chitosan.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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