Efficient multigram procedure for the synthesis of large hydrazone-linked molecular cages-Reference-Cited by-同舟云学术

Efficient multigram procedure for the synthesis of large hydrazone-linked molecular cages

Published:2023 Issue:16 Volume:10 Page:3965-3974
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Vestrheim Olav¹²,Schenkelberg Mica E.¹²,Dai Qingsheng²^ORCID,Schneebeli Severin T.¹²^ORCID

Affiliation:

1. Departments of Industrial & Physical Pharmacy and Chemistry, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907, USA

2. Department of Chemistry and Materials Science Program, University of Vermont, 82 University Place, Burlington, VT 05405, USA

Abstract

An efficient pathway to synthesize covalent hydrazone-linked molecular tetrahedra is reported. Our new synthesis enabled us to create a family of hydrolytically stable organic molecular cages with large openings required to bind complex guests.

Funder

National Institute of General Medical Sciences

National Science Foundation

National Institute of Food and Agriculture

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D3QO00480E

Reference40 articles.

1. Template-Directed Synthesis of Molecular Nanorings and Cages

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3. Organic Imine Cages: Molecular Marriage and Applications

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5. Design and Applications of Water-Soluble Coordination Cages

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