New structures, chemotaxonomic significance and COX-2 inhibitory activities of cassane-type diterpenoids from the seeds of Caesalpinia minax
Author:
Affiliation:
1. Institute of Traditional Chinese Medicine and Natural Products
2. College of Pharmacy
3. Jinan University
4. Guangzhou 510632
5. P. R. China
6. Institute for Tumor Immunology
7. Ludong University School of Life Sciences
8. Yantai
Abstract
Eleven new cassane-type diterpenoids, and twelve known compounds were isolated from the seeds of Caesalpinia minax Hance. Some of them displayed potent inhibitory activity against COX-2 through hydrogen bonding and π–π interactions.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA14221K
Reference23 articles.
1. Structure and antiviral properties of macrocaesalmin, a novel cassane furanoditerpenoid lactone from the seeds of Caesalpinia minax Hance
2. Cassane- and Norcassane-Type Diterpenes from Caesalpinia crista of Indonesia and Their Antimalarial Activity against the Growth of Plasmodium falciparum
3. Caesaljapin, a cassane diterpenoid from Caesalpinia decapetala var. Japonica
4. Evidence of the involvement of biogenic amines in the antinociceptive effect of a vouacapan extracted from Pterodon polygalaeflorus Benth
5. Syntesis of 6α, 7β-di-hydroxyvouacapan-17β-oic acid Derivatives. Parte I: Hydroxamic Acid and Amide Derivatives
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