A novel H2S releasing-monastrol hybrid (MADTOH) inhibits L-type calcium channels-Reference-Cited by-同舟云学术

A novel H2S releasing-monastrol hybrid (MADTOH) inhibits L-type calcium channels

Published:2021 Issue:2 Volume:45 Page:671-678
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Braga Taniris Cafiero¹²³⁴,de Jesus Itamar Couto Guedes⁵⁶²³⁴,Soares Kathleen Viveiros¹²³⁴,Guatimosim Silvia⁵⁶²³⁴,da Silva Neto Leonardo⁷⁸⁴,da-Silva Cristiane Jovelina⁹⁶²³⁴,Modolo Luzia Valentina⁹⁶²³⁴,Menezes Filho José Evaldo Rodrigues¹⁰¹¹⁴,Rhana Paula¹²⁶²³⁴,Cruz Jader Santos¹²⁶²³⁴,de Fátima Ângelo¹²³⁴^ORCID

Affiliation:

1. Departamento de Química

2. Universidade Federal de Minas Gerais

3. Belo Horizonte

4. Brazil

5. Departamento de Fisiologia e Biofísica

6. Instituto de Ciências Biológicas

7. Instituto Federal Farroupilha

8. Alegrete

9. Departamento de Botânica

10. Faculdades Integradas de Sergipe

11. Tobias Barreto

12. Departamento de Bioquímica e Imunologia

Abstract

A new alleged monastrol-H₂S releasing hybrid, named MADTOH, was designed based on the structure of monastrol (M) and 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (ADTOH) and synthesized in 7.8% overall yield.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de Minas Gerais

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D0NJ04415F

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1. Cardiac excitation–contraction coupling