Orobol from enzyme biotransformation attenuates <i>Dermatophagoides farinae</i>-induced atopic dermatitis-like symptoms in NC/Nga mice-Reference-Cited by-同舟云学术

Orobol from enzyme biotransformation attenuates Dermatophagoides farinae-induced atopic dermatitis-like symptoms in NC/Nga mice

Published:2022 Issue:8 Volume:13 Page:4592-4599
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Lee Chang Hyung¹²^ORCID,Yang Hee²,Yoon Park Jung Han²,Kim Jong-Eun³^ORCID,Lee Ki Won¹²⁴^ORCID

Affiliation:

1. Biomodulation Major, Department of Agricultural Biotechnology, Seoul National University, Seoul 08826, Republic of Korea

2. Bio-MAX Institute, Seoul National University, Seoul, 08826, Republic of Korea

3. Department of Food Science and Technology, Korea National University of Transportation, Jeungpyeong 27909, Republic of Korea

4. Advanced Institute of Convergence Technology, Seoul National University, 8 Gyeonggi-do, 16229, Suwon, Republic of Korea

Abstract

Orobol, a metabolite of genistein, is rare in natural soybean. It was found to have strong preventive and curative effects on AD in animal and cell models, and is superior to the natural isoflavone, genistein.

Funder

National Research Foundation of Korea

Ministry of SMEs and Startups

Korea National University of Transportation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO04362E

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