The synthesis of the very long chain polyunsaturated fatty acid (VLC-PUFA) 32:6 n-3-Reference-Cited by-同舟云学术

The synthesis of the very long chain polyunsaturated fatty acid (VLC-PUFA) 32:6 n-3

Published:2021 Issue: Volume: Page:
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wade Alexander¹²³⁴,Rallabandi Rameshu¹²³⁴^ORCID,Lucas Steven¹²³⁴,Oberg Catrina¹²³⁴^ORCID,Gorusupudi Aruna⁵⁶⁷²³^ORCID,Bernstein Paul S.⁵⁶⁷²³,Rainier Jon D.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Utah

3. Salt Lake City

4. USA

5. Department of Ophthalmology and Visual Sciences

6. 65 Mario Capecchi Drive

7. Moran Eye Center

Abstract

This work describes the synthesis of the VLC-PUFA 32:6 n-3 along with its uptake into mouse retinal tissue.

Funder

University of Utah

Foundation Fighting Blindness

Knights Templar Eye Foundation

National Science Foundation

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00491C

Reference25 articles.

1. Very long chain fatty acids in higher animals—A review

2. Role of long-chain and very-long-chain polyunsaturated fatty acids in macular degenerations and dystrophies

3. A novel group of very long chain polyenoic fatty acids in dipolyunsaturated phosphatidylcholines from vertebrate retina.

4. The occurrence of polyenoic very long chain fatty acids with greater than 32 carbon atoms in molecular species of phosphatidylcholine in normal and peroxisome-deficient (Zellweger's syndrome) brain

5. Phospholipid species containing long and very long polyenoic fatty acids remain with rhodopsin after hexane extraction of photoreceptor membranes

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