Design, synthesis and anticancer activity of dihydropyrimidinone–semicarbazone hybrids as potential human DNA ligase 1 inhibitors
Author:
Affiliation:
1. Medicinal and Process Chemistry Division
2. CSIR-Central Drug Research Institute
3. Lucknow
4. India
5. Molecular and Structural Biology Division
6. Pharmacokinetics and Metabolism Division
Abstract
A series of rationally designed new class of hLig1 inhibitors with potentin vitroanti-cancer properties is presented.
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/MD/C6MD00447D
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