Post-digestion stabilization of osmium enables quantification by ICP-MS in cell culture and tissue-Reference-Cited by-同舟云学术

Post-digestion stabilization of osmium enables quantification by ICP-MS in cell culture and tissue

Published:2017 Issue:13 Volume:142 Page:2327-2332
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Klose Matthias H. M.¹²³⁴⁵,Hejl Michaela¹²³⁴,Heffeter Petra⁵²³⁴⁶^ORCID,Jakupec Michael A.¹²³⁴⁵^ORCID,Meier-Menches Samuel M.¹²³⁴⁵^ORCID,Berger Walter⁵²³⁴⁶^ORCID,Keppler Bernhard K.¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Inorganic Chemistry

2. University of Vienna

3. Vienna

4. Austria

5. Research Cluster ‘Translational Cancer Therapy Research’

6. Institute of Cancer Research

Abstract

Sample preparation procedures were adapted to reliably quantify an orally active osmium anticancer compound in the organs of treated mice and in cellular accumulation experiments by inductively coupled plasma-mass spectrometry.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/AN/C7AN00350A

Reference23 articles.

1. Cytotoxicity, Hydrophobicity, Uptake, and Distribution of Osmium(II) Anticancer Complexes in Ovarian Cancer Cells

2. Ruthenium− and Osmium−Arene Complexes of 2-Substituted Indolo[3,2-c]quinolines: Synthesis, Structure, Spectroscopic Properties, and Antiproliferative Activity

3. Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex

4. Biological activity of ruthenium and osmium arene complexes with modified paullones in human cancer cells

5. Metal–Arene Complexes with Indolo[3,2-c]-quinolines: Effects of Ruthenium vs Osmium and Modifications of the Lactam Unit on Intermolecular Interactions, Anticancer Activity, Cell Cycle, and Cellular Accumulation

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