Affiliation:
1. Sygnature Discovery, BioCity Nottingham NG1 1GR UK a.jordan@sygnaturediscovery.com
2. Blue Burgundy Ltd Ampthill Bedfordshire MK45 2AD UK
Abstract
The discovery, optimisation and manufacture of medicines are processes underpinned by synthesis on scales from milligrams to tonnes; synthetic or semi-synthetic pharmaceuticals remain the cornerstones of modern medicines, as chemists innovate to deliver molecules to address contemporary challenges. This chapter reviews the crucial impact of synthesis, considering changing practices, contemporary developments in technology and methodology, and provides a view to how things may develop in future.
Publisher
The Royal Society of Chemistry