Short-T2 Imaging Applications in Pharmaceutical Research

Abstract

This chapter describes magnetic resonance imaging (MRI) techniques designed specifically for the imaging of short-lifetime (broad-line) materials and their application in pharmaceutical research. Ultrashort echo time, zero echo time, and constant time imaging methods are compared, and selected instances from the literature are described. Short-lifetime MRI methods are not widely employed in the pharmaceutical literature but have provided complementary information and sometimes unique mechanistic insight where applied. There is certainly scope for fruitful applications and continued methods development in this area of materials MRI.