A diastereoselective approach to amino alcohols and application for divergent synthesis of dolastatin 10
Author:
Affiliation:
1. Institutes of Biomedical Sciences and School of Pharmacy
2. Fudan University
3. Shanghai
4. China
5. Shanghai Institute of Organic Chemistry
6. Chinese Academy of Sciences
7. Shanghai 200032
Abstract
A diastereoselective approach to obtain amino alcohols through SmI2-induced radical addition and divergent synthesis of dolastatin 10 are described.
Funder
National Natural Science Foundation of China
Beijing Technology and Business University
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/QO/C9QO01292C
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