Concurrent photothermal therapy and photodynamic therapy for cutaneous squamous cell carcinoma by gold nanoclusters under a single NIR laser irradiation

Author:

Liu Pei1234ORCID,Yang Weitao12345,Shi Lei1234ORCID,Zhang Haiyan1234ORCID,Xu Yan12345ORCID,Wang Peiru1234ORCID,Zhang Guolong1234ORCID,Chen Wei R.678910ORCID,Zhang Bingbo12345ORCID,Wang Xiuli1234ORCID

Affiliation:

1. Institute of Photomedicine, Shanghai Skin Disease Hospital

2. Tongji University School of Medicine

3. Shanghai

4. P. R. China

5. Tongji University Cancer Center, The Institute for Biomedical Engineering & Nano Science

6. Biophotonics Research Laboratory

7. Center for Interdisciplinary Biomedical Education and Research

8. University of Central Oklahoma

9. Edmond

10. USA

Abstract

The concurrent photothermal and photodynamic therapy of cutaneous squamous cell carcinoma by a single drug of Au25(Capt)18nanoclusters is demonstrated, together with a preliminary immune response study conducted under a single NIR laser irradiation.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Science and Technology Commission of Shanghai Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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