Discovery, stereospecific characterization and peripheral modification of 1-(pyrrolidin-1-ylmethyl)-2-[(6-chloro-3-oxo-indan)-formyl]-1,2,3,4-tetrahydroisoquinolines as novel selective κ opioid receptor agonists-Reference-Cited by-同舟云学术

Discovery, stereospecific characterization and peripheral modification of 1-(pyrrolidin-1-ylmethyl)-2-[(6-chloro-3-oxo-indan)-formyl]-1,2,3,4-tetrahydroisoquinolines as novel selective κ opioid receptor agonists

Published:2015 Issue:20 Volume:13 Page:5656-5673
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Gan Zong-Jie¹²³⁴,Wang Yu-Hua⁵⁶⁷⁴⁸,Xu Yun-Gen¹²³⁴⁹,Guo Ting¹²³⁴,Wang Jun⁹²³⁴,Song Qiao¹²³⁴,Xu Xue-Jun⁵⁶⁷⁴,Hu Shi-Yuan⁹²³⁴,Wang Yu-Jun⁵⁶⁷⁴,Wang De-Chuan⁹²³⁴,Sun De-Zhu¹⁰²³⁴,Zhang Di¹²³⁴,Xi Tao⁹²³⁴,Li Hao-Dong¹¹¹²⁴,Zhang Hai-Bo¹¹¹²⁴,Hang Tai-Jun¹⁰²³⁴,Lu Hong-Guo¹¹¹²⁴,Liu Jing-Gen⁵⁶⁷⁴

Affiliation:

1. Jiangsu Key Laboratory of Drug Design and Optimization

2. China Pharmaceutical University

3. Nanjing 210009

4. China

5. Shanghai Institute of Materia Medica

6. Chinese Academy of Sciences

7. Shanghai 201203

8. School of Pharmacy

9. Department of Medicinal Chemistry

10. Department of Pharmaceutical Analysis

11. Yangze River Pharmaceutical Group