Design and synthesis of lipid-mimetic cationic iridium complexes and their liposomal formulation for in vitro and in vivo application in luminescent bioimaging

Author:

Shakirova Julia R.1234ORCID,Sadeghi Amir56789,Koblova Alla A.1234ORCID,Chelushkin Pavel S.1234ORCID,Toropainen Elisa56789,Tavakoli Shirin101112139,Kontturi Leena-Stiina101112139,Lajunen Tatu101112139ORCID,Tunik Sergey P.1234ORCID,Urtti Arto12345ORCID

Affiliation:

1. St. Petersburg State University

2. Institute of Chemistry

3. 198504 St. Petersburg

4. Russia

5. School of Pharmacy

6. Faculty of Health Sciences

7. University of Eastern Finland

8. 70211 Kuopio

9. Finland

10. Drug Research Program

11. Faculty of Pharmacy

12. University of Helsinki

13. 00710 Helsinki

Abstract

Novel lipoidal Ir(iii) phosphorescent labels were embedded into liposomes and used for imaging in cells and animals.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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