Allicin suppressed <i>Escherichia coli</i>-induced urinary tract infections by a novel MALT1/NF-κB pathway-Reference-Cited by-同舟云学术

Allicin suppressed Escherichia coli-induced urinary tract infections by a novel MALT1/NF-κB pathway

Published:2022 Issue:6 Volume:13 Page:3495-3511
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Chang Zhenglin¹²^ORCID,An Lingyue¹²,He Zhican¹²,Zhang Yuyan³,Li Shujue²,Lei Min¹²,Xu Peng¹²,Lai Yongchang⁴^ORCID,Jiang Zheng¹²,Huang Yapeng¹²,Duan Xiaolu²,Wu Wenqi¹²

Affiliation:

1. Department of Urology, the Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, 510260, China

2. Department of Urology, the First Affiliated Hospital of Guangzhou Medical University, Guangdong Key Laboratory of Urology, Guangzhou, 510230, China

3. Guangzhou Institute of Dermatology, Guangzhou, 510095, China

4. Department of Urology, Shenzhen Shockwave Lithotripsy Research Institute, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong 518033, China

Abstract

Our experiments revealed that the therapeutic effects of allicin against E. coli induced urinary inflammation were characterized by the restoration of the highly expressed MALT1, the activated AKT/NF-κB pathway, and excessive release of cytokines.

Funder

Department of Education of Guangdong Province

Natural Science Foundation of Guangdong Province

Guangdong Medical Research Foundation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO03853B

Reference53 articles.