Neophathalides A and B, two pairs of unusual phthalide analog enantiomers from Ligusticum chuanxiong-Reference-Cited by-同舟云学术

Neophathalides A and B, two pairs of unusual phthalide analog enantiomers from Ligusticum chuanxiong

Published:2020 Issue:28 Volume:18 Page:5453-5457
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Xu¹²³⁴⁵,Yan Hai-Wei¹²³⁴⁵,Feng Zi-Ming¹²³⁴⁵,Yang Ya-Nan¹²³⁴⁵^ORCID,Jiang Jian-Shuang¹²³⁴⁵,Zhang Pei-Cheng¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines

2. Institute of Materia Medica

3. Chinese Academy of Medical Sciences and Peking Union Medical College

4. Beijing 100050

5. People’s Republic of China

Abstract

Two pairs of unusual phthalide analog enantiomers, (+)- and (−)-neophathalides A and B [(+)- and (−)-1 and 2], were isolated from the rhizome of Ligusticum chuanxiong Hort.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01014F

Reference17 articles.

1. Phthalides and Phthalans: Synthetic Methodologies and Their Applications in the Total Synthesis

2. l-3-n-butylphthalide alleviates hydrogen peroxide-induced apoptosis by PKC pathway in human neuroblastoma SK-N-SH cells

3. l-3-n-Butylphthalide ameliorates β-amyloid-induced neuronal toxicity in cultured neuronal cells

4. Relaxation effects of ligustilide and senkyunolide A, two main constituents of Ligusticum chuanxiong, in rat isolated aorta

5. Phthalide Lactones fromLigusticum chuanxiongInhibit Lipopolysaccharide-Induced TNF-α Production and TNF-α-Mediated NF-κB Activation

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