Copper-catalyzed tandem N-arylation/condensation: synthesis of quinazolin-4(3H)-ones from 2-halobenzonitriles and amides-Reference-Cited by-同舟云学术

Copper-catalyzed tandem N-arylation/condensation: synthesis of quinazolin-4(3H)-ones from 2-halobenzonitriles and amides

Published:2014 Issue:84 Volume:4 Page:44811-44814
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Chai Hongxin¹²³,Li Jiarong¹²³,Yang Liupan⁴⁵⁶,Lu Hongyan¹²³,Qi Zhang¹²³,Shi Daxin¹²³

Affiliation:

1. School of Chemical Engineering and Environment

2. Beijing Institute of Technology

3. Beijing 100081, China

4. Jiangsu Hengrui Medicine Co., Ltd

5. Lianyungang Eco & Tech Development Zone

6. , China

Abstract

A novel, straightforward and practical copper-catalyzed domino protocol for synthesis of quinazolin-4(3H)-one derivatives from commercially available 2-halobenzonitriles and amides was successfully developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA08031A

Reference61 articles.

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5. Recent advances in the structural library of functionalized quinazoline and quinazolinone scaffolds: Synthetic approaches and multifarious applications

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