Cascade C–N bond cleavage of amides/intramolecular amination reactions: an atom economical way to α-cabolin-4-ones-Reference-Cited by-同舟云学术

Cascade C–N bond cleavage of amides/intramolecular amination reactions: an atom economical way to α-cabolin-4-ones

Published:2021 Issue:3 Volume:8 Page:579-583
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Wang Ye¹²³⁴,Zheng Zhong¹²³⁴^ORCID,Yuan Yang¹²³⁴^ORCID,Wang Mengdan¹²³⁴,Guo Zixia¹²³⁴,Jiang Yuan-Ye⁵⁶⁷⁴^ORCID,Bai Li-Ping⁸⁹¹⁰¹¹¹²^ORCID,Li Yanzhong¹²³⁴^ORCID

Affiliation:

1. School of Chemistry and Molecular Engineering

2. East China Normal University

3. Shanghai

4. China

5. School of Chemistry and Chemical Engineering

6. Qufu Normal University

7. Qufu

8. State Key Laboratory of Quality Research in Chinese Medicine

9. and Macau Institute for Applied Research in Medicine and Health

10. Macau University of Science and Technology

11. Taipa

12. Macau

Abstract

A novel one-pot procedure for the synthesis of 2,3-disubstituted α-carbolin-4-ones through successive C–N bond cleavage and intramolecular amination reactions involving a 1,2-acyl migration has been developed.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Fundo para o Desenvolvimento das Ciências e da Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D0QO01257B

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1. Jusbetonin, the First Indolo[3,2-b]quinoline Alkaloid Glycoside, from Justicia betonica