p-Nitrobenzenesulfonamides and their fluorescent dansylsulfonamides derived from N-alkylated o-(purine-methyl)anilines as novel antitumour agents

Author:

Morales Fátima12345,Conejo-García Ana12345,Ramírez Alberto678910,Morata Cynthia114121013,Marchal Juan Antonio114121013,Campos Joaquín M.12345

Affiliation:

1. Department of Pharmaceutical and Organic Chemistry

2. c/Campus de Cartuja s/n

3. Faculty of Pharmacy

4. University of Granada

5. 18081 Granada

6. Department of Health Sciences

7. Paraje de las Lagunillas s/n

8. University of Jaén

9. Jaén

10. Spain

11. Biopathology and Medicine Regenerative Institute (IBIMER)

12. Granada

13. Biosanitary Institute of Granada (ibs.GRANADA)

Abstract

10 shows an IC50 = 134 nM (A-375). Its dansyl analogue is absorbed (P.O.) accumulating mainly in liver and kidney.

Funder

Instituto de Salud Carlos III

Ministerio de Educación, Cultura y Deporte

European Union Agency for Network and Information Security

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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