Candida albicans zincophore and zinc transporter interactions with Zn(ii) and Ni(ii)

Author:

Łoboda D.1234,Rowińska-Żyrek M.1234ORCID

Affiliation:

1. Faculty of Chemistry

2. University of Wroclaw

3. 50383 Wroclaw

4. Poland

Abstract

The Zrt1 transporter binds Zn(ii) with higher affinity than the Pra1 zincophore, allowing efficient zinc transfer into the fungal cell.

Funder

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Reference24 articles.

1. Copper- and zinc-containing superoxide dismutase (Cu/ZnSOD) is required for the protection of Candida albicans against oxidative stresses and the expression of its full virulence

2. M. Monod , O.Jousson and U.Reichard , Aspergillus fumigatus Secreted Proteasesed , in Aspergillus fumigatus and Aspergillosis , ed. J. Latgé and W. Steinbach , ASM Press , 2009 , pp. 87–106

3. Fungal Proteases and Their Pathophysiological Effects

4. I. Bremner and P. M.May , Systemic Interactions of Zinc , in Zinc in Human Biology. ILSI Human Nutrition Reviews , ed. C. F. Mills , Springer , London , 1989

5. Nutritional immunity beyond iron: a role for manganese and zinc

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