Gram-scale synthesis of a neodymium chelate as a spectral CT and second near-infrared window imaging agent for visualizing the gastrointestinal tract in vivo

Author:

Zhuang Pengrui1234,Xiang Ke1234,Meng Xiangxi5674ORCID,Wang Guohe1234,Li Ziyuan89104,Lu Yanye89104,Kan Di1234,Zhang Xuejun1234,Sun Shao-Kai1234ORCID

Affiliation:

1. Department of Medical imaging

2. Tianjin Medical University

3. Tianjin 300203

4. China

5. Department of Nuclear Medicine

6. Peking University Cancer Hospital & Institute

7. Beijing 100142

8. Department of Biomedical Engineering

9. Peking University

10. Beijing 100871

Abstract

A facile and green method was developed to fabricate Nd-DTPA on a large scale without byproducts for CT/spectral CT and NIR II fluorescence imaging of the gastrointestinal tract in vivo.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Tianjin City

Young Elite Scientists Sponsorship Program by Tianjin

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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