Combined homogeneous and heterogeneous hydrogenation to yield catalyst-free solutions of parahydrogen-hyperpolarized [1-<sup>13</sup>C]succinate-Reference-Cited by-同舟云学术

Combined homogeneous and heterogeneous hydrogenation to yield catalyst-free solutions of parahydrogen-hyperpolarized [1-¹³C]succinate

Published:2023 Issue:62 Volume:59 Page:9509-9512
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Eills James¹²³^ORCID,Picazo-Frutos Román²³,Burueva Dudari B.⁴^ORCID,Kovtunova Larisa M.⁴⁵,Azagra Marc¹,Marco-Rius Irene¹^ORCID,Budker Dmitry²³⁶^ORCID,Koptyug Igor V.⁴^ORCID

Affiliation:

1. Institute for Bioengineering of Catalonia, Barcelona Institute of Science and Technology, Barcelona 08028, Spain

2. Helmholtz-Institut Mainz, GSI Helmholtzzentrum für Schwerionenforschung, Mainz 55128, Germany

3. Institute for Physics, Johannes Gutenberg-Universität Mainz, Mainz 55099, Germany

4. International Tomography Center SB RAS, Novosibirsk 630090, Russia

5. Boreskov Institute of Catalysis SB RAS, Novosibirsk 630090, Russia

6. Department of Physics, University of California, Berkeley, CA 94720-7300, USA

Abstract

We show that catalyst-free aqueous solutions of hyperpolarized [1-13C]succinate can be produced using parahydrogen-induced polarization (PHIP) and a combination of homogeneous and heterogeneous catalytic hydrogenation reactions.

Funder

H2020 Marie Skłodowska-Curie Actions

Deutsche Forschungsgemeinschaft

European Social Fund

Russian Science Foundation

Ministerio de Ciencia e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01803B

Reference35 articles.

1. Spin Hyperpolarization in Modern Magnetic Resonance

2. Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1- 13 C]Pyruvate

3. Parahydrogen‐Based Hyperpolarization for Biomedicine

4. Production of highly concentrated and hyperpolarized metabolites within seconds in high and low magnetic fields

5. Real-Time Nuclear Magnetic Resonance Detection of Fumarase Activity Using Parahydrogen-Hyperpolarized [1-13C]Fumarate