Formation of organic molecular nanocrystals under soft confinement
Author:
Affiliation:
1. Novartis-MIT Center for Continuous Manufacturing and Department of Chemical Engineering
2. Massachusetts Institute of Technology
3. Cambridge, USA
4. Department of Chemistry and Francis Bitter Magnet Laboratory
Abstract
We report the use of a novel solution impregnation method to form nanocrystals in polymer matrices with various microstructures in order to study the structure of the confined nanocrystals and the role of soft confinement and polymer chemistry on the nucleation process of nano-sized crystals.
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/CE/C5CE01202C
Reference39 articles.
1. Drug Nanoparticles: Formulating Poorly Water-Soluble Compounds
2. Polymorphism control of nanosized glycine crystals on engineered surfaces
3. Formation of Nanosized Organic Molecular Crystals on Engineered Surfaces
4. Production and Characterization of Carbamazepine Nanocrystals by Electrospraying for Continuous Pharmaceutical Manufacturing
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