A novel sulfate-bridged binuclear copper(ii) complex: structure, optical, ADMET and in vivo approach in a murine model of bone metastasis

Author:

Hchicha Khouloud12345,Korb Marcus678910,Badraoui Riadh1112131415,Naïli Houcine12345ORCID

Affiliation:

1. Laboratoire Physico-Chimie de l’Etat Solide

2. Département de Chimie

3. Faculté des Sciences de Sfax

4. Université de Sfax

5. Tunisia

6. The University of Western Australia

7. Faculty of Sciences

8. School of Molecular Sciences

9. Perth

10. Australia

11. Laboratory of General Biology

12. Department of Biology

13. University of Ha’il

14. 81451 Ha’il

15. Saudi Arabia

Abstract

A novel complex, formulated as [Cu23-SO4)2(C4H6N2)4], showed significant ameliorative effects on tumor osteolytic lesions in malignant Walker 256/B breast cancer-induced bone metastases.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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