Design, synthesis, molecular docking and anti-proliferative activity of novel phenothiazine containing imidazo[1,2-<i>a</i>]pyridine derivatives against MARK4 protein-Reference-Cited by-同舟云学术

Design, synthesis, molecular docking and anti-proliferative activity of novel phenothiazine containing imidazo[1,2-a]pyridine derivatives against MARK4 protein

Published:2024 Issue:6 Volume:15 Page:1942-1958
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Bhakta Avijit¹^ORCID,Mukhtar Sayeed²,Anwar Saleha³,Haider Shaista⁴,Alahmdi Mohammed Issa²,Parveen Humaira²,Alsharif Meshari A.⁵,Wani Mohmmad Younus⁶,Chakrabarty Anindita⁴,Hassan Md. Imtaiyaz³^ORCID,Ahmed Naseem¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee-247 667 U.K., India

2. Department of Chemistry, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia

3. Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia, New Delhi, India

4. Department of Life Sciences, Shiv Nadar University, Uttar Pradesh 201314, India

5. Chemistry Department, Faculty of Applied Science, Umm Al-Qura University, Makkah, Saudi

6. Department of Chemistry, College of Science, University of Jeddah, 21589 Jeddah, Saudi Arabia

Abstract

A series of novel phenothiazine-containing imidazo[1,2-a]pyridine derivatives were designed and synthesized under metal-free conditions in excellent yield.

Funder

University of Tabuk

Department of Science and Technology, Ministry of Science and Technology, India

Indian Institute of Technology Roorkee

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D4MD00059E

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4. Structure and function of polarity‐inducing kinase family MARK/Par‐1 within the branch of AMPK/Snf1‐related kinases

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