A lysozyme corona complex for the controlled pharmacokinetic release of probucol from mesoporous silica particles
Author:
Affiliation:
1. Dpt. Molecular Sciences
2. Macquarie University
3. Sydney
4. Australia
5. Centre for Nanoscale and BioPhotonics
Abstract
Mesoporous silica particles (MSPs) enhance and allow to control the release kinetics of poorly soluble compound probucol (PB) under the influence of a pore-blocking lysozyme protein corona.
Funder
Australian Research Council
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM00445F
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1. In vivo oral toxicological evaluation of mesoporous silica particles
2. Enhanced absorption of the poorly soluble drug fenofibrate by tuning its release rate from ordered mesoporous silica
3. Ordered Mesoporous Silica Material SBA-15: A Broad-Spectrum Formulation Platform for Poorly Soluble Drugs
4. Probing the Amorphous State of Pharmaceutical Compounds Within Mesoporous Material Using Pair Distribution Function Analysis
5. Multifunctional Mesoporous Silica Nanoparticles as a Universal Platform for Drug Delivery
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