Covalent and non-covalent coupling of a Au102 nanocluster with a fluorophore: energy transfer, quenching and intracellular pH sensing-Reference-Cited by-同舟云学术

Covalent and non-covalent coupling of a Au102 nanocluster with a fluorophore: energy transfer, quenching and intracellular pH sensing

Published:2021 Issue:23 Volume:3 Page:6649-6658
ISSN:2516-0230
Container-title:Nanoscale Advances
language:en
Short-container-title:Nanoscale Adv.

Author:

Hulkko Eero¹,Lahtinen Tanja¹^ORCID,Marjomäki Varpu²,Pohjolainen Emmi³,Saarnio Ville¹,Sokolowska Karolina¹,Ajitha Ardra¹,Kuisma Mikael¹,Lehtovaara Lauri¹,Groenhof Gerrit¹,Häkkinen Hannu¹³^ORCID,Pettersson Mika¹^ORCID

Affiliation:

1. Department of Chemistry, Nanoscience Center, University of Jyväskylä, P.O. Box 35, FI-40014, Finland

2. Department of Biology and Environmental Science, Nanoscience Center, University of Jyväskylä, P.O. Box 35, FI-40014, Finland

3. Department of Physics, Nanoscience Center, University of Jyväskylä, P.O. Box 35, FI-40014, Finland

Abstract

A covalently bound hybrid between an atomically precise gold nanocluster and a fluorescent dye is loaded into cells via endocytosis. Acidification of the endosomes activates fluorescence, enabling optical pH sensing inside live cells.

Funder

Academy of Finland

Jane ja Aatos Erkon Säätiö

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NA/D1NA00368B

Reference39 articles.

1. T.Tsukuda , and H.Häkkinen , Protected Metal Clusters: from Fundamentals to Applications Elsevier , 2015

2. Atomically Precise Colloidal Metal Nanoclusters and Nanoparticles: Fundamentals and Opportunities