In vivo biodistribution of kinetically stable Pt2L4 nanospheres that show anti-cancer activity-Reference-Cited by-同舟云学术

In vivo biodistribution of kinetically stable Pt₂L₄ nanospheres that show anti-cancer activity

Published:2023 Issue:25 Volume:14 Page:6943-6952
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Bobylev Eduard O.¹^ORCID,Knol Renzo A.²^ORCID,Mathew Simon¹^ORCID,Poole David A.¹^ORCID,Kotsogianni Ioli³,Martin Nathaniel I.³^ORCID,de Bruin Bas¹^ORCID,Kros Alexander²^ORCID,Reek Joost N. H.¹^ORCID

Affiliation:

1. van ‘t Hoff Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The Netherlands

2. Dept. of Supramolecular & Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300 RA, Leiden, The Netherlands

3. Biological Chemistry Group, Institute of Biology Leiden, Leiden University, 2333 BE Leiden, The Netherlands

Abstract

Two fluorescent, stable Pt2L4 nanocages are developed. Pt2L4 have alternated cytotoxicity and display diverse cell uptake in vivo making the versitale nanocages interesting candidates for further delivery and toxicity studies.

Funder

Universiteit van Amsterdam

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC01086D

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