Thiochromenocarbazole imide-based photosensitizers decorated with carbonic anhydrase inhibitors for the targeted treatment of hypoxic tumours-Reference-Cited by-同舟云学术

Thiochromenocarbazole imide-based photosensitizers decorated with carbonic anhydrase inhibitors for the targeted treatment of hypoxic tumours

Published:2024 Issue:10 Volume:5 Page:4172-4177
ISSN:2633-5409
Container-title:Materials Advances
language:en
Short-container-title:Mater. Adv.

Author:

Merabti Amina¹²,Sánchez Darío Puchán³,Nocentini Alessio⁴,Ali Lamiaa M. A.²^ORCID,Nguyen Christophe²^ORCID,Durand Denis²,Hamon Kathleen²,Ghanem Tatiana³,Arnoux Philippe⁵^ORCID,Josse Pierre³,Frochot Céline⁵^ORCID,Zalubovskis Raivis⁶^ORCID,Richeter Sébastien¹^ORCID,Gary-Bobo Magali²^ORCID,Supuran Claudiu T.⁴^ORCID,Cabanetos Clément³^ORCID,Winum Jean-Yves²^ORCID,Clément Sébastien¹^ORCID

Affiliation:

1. ICGM, Univ Montpellier, CNRS, ENSCM, Montpellier, France

2. IBMM, Univ Montpellier, CNRS, ENSCM, Montpellier, France

3. Univ Angers, CNRS, MOLTECH-ANJOU, SFR MATRIX, F-49000 Angers, France

4. NEUROFARBA Department, Pharmaceutical and Nutraceutical Section, University of Florence, Via U. Schiff 6, 50019 Sesto Fiorentino, Firenze, Italy

5. Université de Lorraine, CNRS, LRGP, F-54000 Nancy, France

6. Latvian Institute of Organic Synthesis, Aizkraukles 21, 1006, Riga, Latvia

Abstract

A series of thiochromenocarbazole imide (TCI) photosensitizers featuring carbonic anhydrase inhibitors (CAi) was designed to alleviate the consequences of PDT-induced hypoxia by merging the advantages of hCA IX knockdowns with PDT.

Funder

Université de Montpellier

Centre National de la Recherche Scientifique

Ligue Contre le Cancer

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MA/D3MA00926B

Reference39 articles.

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