Elucidating the 3D structures of Al(iii)–Aβ complexes: a template free strategy based on the pre-organization hypothesis-Reference-Cited by-同舟云学术

Elucidating the 3D structures of Al(iii)–Aβ complexes: a template free strategy based on the pre-organization hypothesis

Published:2017 Issue:7 Volume:8 Page:5041-5049
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Mujika Jon I.¹²³⁴^ORCID,Rodríguez-Guerra Pedregal Jaime⁵⁶⁷⁴^ORCID,Lopez Xabier¹²³⁴,Ugalde Jesus M.¹²³⁴,Rodríguez-Santiago Luis⁵⁶⁷⁴^ORCID,Sodupe Mariona⁵⁶⁷⁴,Maréchal Jean-Didier⁵⁶⁷⁴

Affiliation:

1. Kimika Fakultatea

2. Euskal Herriko Unibertsitatea (UPV/EHU) and Donostia International Physics Center (DIPC)

3. 20080 Donostia

4. Spain

5. Departament de Química

6. Universitat Autònoma de Barcelona

7. Bellaterra 08193

Abstract

We present a novel strategy to generate accurate 3D models of Al(iii)–Aβ complexes, which circumvents first principles simulations of metal binding to peptides of Aβ.

Funder

Generalitat de Catalunya

Eusko Jaurlaritza

Ministerio de Economía y Competitividad

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC01296A

Reference48 articles.

1. Amyloid β-Protein Assembly and Alzheimer Disease