Synthesis of a dimer of the repeating unit of type Ia group BStreptococcusextracellular capsular polysaccharide and immunological evaluations of related protein conjugates-Reference-Cited by-同舟云学术

Synthesis of a dimer of the repeating unit of type Ia group BStreptococcusextracellular capsular polysaccharide and immunological evaluations of related protein conjugates

Published:2019 Issue:16 Volume:6 Page:2833-2838
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liao Guochao¹²³⁴⁵^ORCID,Guo Jiatong⁶⁷⁸⁹⁶,Yang Deying¹²³⁴⁵,Zhou Zhifang⁶⁷⁸⁹¹⁰,Liu Zhongqiu¹²³⁴⁵,Guo Zhongwu⁶⁷⁸⁹⁶^ORCID

Affiliation:

1. Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education

2. International Institute for Translational Chinese Medicine

3. Guangzhou University of Chinese Medicine

4. Guangzhou 510006

5. China

6. Department of Chemistry

7. Wayne State University

8. Detroit

9. USA

10. Key Laboratory of Carbohydrate Chemistry & Biotechnology of the Ministry of Education

Abstract

A dimer of the repeating unit of Type Ia group BStreptococcuscapsular polysaccharide was first synthesized, and related protein conjugates induced robust immune responses to carbohydrate antigens.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00486F

Reference39 articles.

1. Group B streptococcus and respiratory syncytial virus immunisation during pregnancy: a landscape analysis

2. Structural and Genetic Diversity of Group B Streptococcus Capsular Polysaccharides

3. Structure of the Type IX Group B Streptococcus Capsular Polysaccharide and Its Evolutionary Relationship with Types V and VII