Impact of copper and iron binding properties on the anticancer activity of 8-hydroxyquinoline derived Mannich bases-Reference-Cited by-同舟云学术

Impact of copper and iron binding properties on the anticancer activity of 8-hydroxyquinoline derived Mannich bases

Published:2018 Issue:47 Volume:47 Page:17032-17045
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Pape Veronika F. S.¹²³⁴⁵^ORCID,May Nóra V.²³⁴⁵^ORCID,Gál G. Tamás²³⁴⁵,Szatmári István⁶⁷⁸⁵,Szeri Flóra¹²³⁴⁵^ORCID,Fülöp Ferenc⁶⁷⁸⁵,Szakács Gergely¹²³⁴⁵^ORCID,Enyedy Éva A.⁹¹⁰⁷⁸⁵^ORCID

Affiliation:

1. Institute of Enzymology

2. Research Centre for Natural Sciences

3. Hungarian Academy of Sciences

4. H-1117 Budapest

5. Hungary

6. Institute of Pharmaceutical Chemistry and Stereochemistry Research Group of Hungarian Academy of Sciences

7. University of Szeged

8. H-6720 Szeged

9. Department of Inorganic and Analytical Chemistry

10. Interdisciplinary Excellence Centre

Abstract

A relationship between pK_a values, binding abilities to copper(ii) and iron(iii) and anticancer activity of 8-hydroxyquinoline derived Mannich bases.

Funder

Nemzeti Kutatási, Fejlesztési és Innovációs Hivatal

Emberi Eroforrások Minisztériuma

Magyar Tudományos Akadémia

European Research Council

U.S. Department of State

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/DT/C8DT03088J