Diagnosis of immunomarkersin vivo viamultiplexed surface enhanced Raman spectroscopy with gold nanostars

Author:

Ou Yu-Chuan1234,Webb Joseph A.1234,O'Brien Christine M.52346ORCID,Pence Isaac J.52346,Lin Eugene C.72348,Paul Eden P.1234,Cole Danielle1234,Ou Shih-Hao1234,Lapierre-Landry Maryse52346,DeLapp Rossane C.9234,Lippmann Ethan S.12345,Mahadevan-Jansen Anita52346,Bardhan Rizia1234ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering

2. Vanderbilt University

3. Nashville

4. USA

5. Department of Biomedical Engineering

6. Vanderbilt Biophotonics Center

7. Department of Radiology and Radiological Sciences

8. Vanderbilt University Institute of Imaging Science

9. Civil and Environmental Engineering

Abstract

In this work biomarkers PD-L1 and EGFR are diagnosed in mouse tumorsin vivoandex vivowith surface-enhanced Raman spectroscopy.

Funder

American Cancer Society

National Institutes of Health

Congressionally Directed Medical Research Programs

National Center for Advancing Translational Sciences

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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