Realisation of small molecule libraries based on frameworks distantly related to natural products-Reference-Cited by-同舟云学术

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Realisation of small molecule libraries based on frameworks distantly related to natural products

Published:2018 Issue:17 Volume:16 Page:3160-3167
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Aimon Anthony¹²³⁴,Karageorgis George¹²³⁴⁵,Masters Jacob¹²³⁴⁵^ORCID,Dow Mark¹²³⁴,Craven Philip G. E.¹²³⁴^ORCID,Ohsten Martin⁶⁷⁸,Willaume Anthony⁶⁷⁸,Morgentin Rémy⁶⁷⁸,Ruiz-Llamas Nicolas⁶⁷⁸,Lemoine Hugues⁶⁷⁸,Kalliokoski Tuomo⁹¹⁰¹¹,Eatherton Andrew J.¹²¹³¹⁴¹⁵⁴,Foley Daniel J.¹²³⁴⁵^ORCID,Marsden Stephen P.¹²³⁴^ORCID,Nelson Adam¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemistry

2. University of Leeds

3. Leeds LS2 9JT

4. UK

5. Astbury Centre for Structural Molecular Biology

6. Edelris

7. F-69003 Lyon

8. France

9. Lead Discovery Center GmbH

10. 44227 Dortmund

11. Germany

12. Medicinal Chemistry

13. Oncology

14. IMED Biotech Unit

15. Cambridge

Abstract

Design and synthesis of compound libraries with focused molecular properties, based on NP-like scaffolds.

Funder

Seventh Framework Programme

Engineering and Physical Sciences Research Council

AstraZeneca

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB00688A

Reference25 articles.

1. Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

2. What Do Medicinal Chemists Actually Make? A 50-Year Retrospective

3. Assessing the Scaffold Diversity of Screening Libraries

4. Structural Diversity of Organic Chemistry. A Scaffold Analysis of the CAS Registry

5. Natural Products as Sources of New Drugs over the Last 25 Years

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