Generating rapamycin analogues by directed biosynthesis: starter acid substrate specificity of mono-substituted cyclohexane carboxylic acids-Reference-Cited by-同舟云学术

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Generating rapamycin analogues by directed biosynthesis: starter acid substrate specificity of mono-substituted cyclohexane carboxylic acids

Published:2006 Issue:22 Volume:4 Page:4071
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Goss Rebecca J. M.,Lanceron Simon E.,Wise Nicola J.,Moss Steven J.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2006/OB/B614519C

Reference19 articles.

1. Rapamune® (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression

2. Identification of TOR Signaling Complexes

3. Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization.

4. TOXICITY OF RAPAMYCIN—A COMPARATIVE AND COMBINATION STUDY WITH CYCLOSPORINE AT IMMUNOTHERAPEUTIC DOSAGE IN THE RAT

5. Total synthesis of rapamycin via a novel titanium-mediated aldol macrocyclization reaction

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