Facile synthesis of the daphnane and tigliane framework by semi-flow tube-based-bubbling photooxidation and diastereoselective conjugate addition-Reference-Cited by-同舟云学术

Facile synthesis of the daphnane and tigliane framework by semi-flow tube-based-bubbling photooxidation and diastereoselective conjugate addition

Published:2020 Issue:14 Volume:7 Page:1862-1868
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Ding Zhengwei¹²³⁴,Liu Zhi¹²³⁴,Tong Guanghu¹²³⁴,Hu Linlin⁵⁶⁷⁴,He Yangqing⁵⁶⁷⁴^ORCID,Bao Yueyun¹²³⁴,Lei Zhouhang¹²³⁴,Zhang Hailong⁸⁹²³⁴,Li Pengfei¹²³⁴¹⁰^ORCID

Affiliation:

1. Frontier Institute of Science and Technology

2. Xi'an Jiaotong University

3. Xi'an

4. China

5. Department of Applied Chemistry

6. Xi'an University of Technology

7. Xi'an 710048

8. Department of Medicinal Chemistry

9. School of Pharmacy

10. Xi'an Key Laboratory of Sustainable Energy Materials Chemistry

Abstract

The common [5-7-6] tricyclic framework in tigliane and daphnane natural diterpenes containing five contiguous stereocenters has been synthesized in 9 steps from readily available starting materials in a completely stereocontrolled manner.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Xi'an Science and Technology Bureau

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00424C

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