Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for neurotoxicity-Reference-Cited by-同舟云学术

Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for neurotoxicity

Published:2019 Issue:2 Volume:11 Page:362-374
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Bianchini Matheus C.¹²³,Gularte Claudia Ortiz Alves¹²³,Nogara Pablo A.⁴⁵³,Krum Bárbara N.⁶⁵³,Gayer Mateus C.¹²³,Bridi Jessika C.⁷⁸⁹^ORCID,Roos Daniel H.¹²³,Roehrs Rafael¹²³,Fachinetto Roselei⁶⁵³,Pinton Simone¹²³,Ávila Daiana S.¹²³,Hirth Frank⁷⁸⁹^ORCID,Rocha João B. T.⁴⁵³^ORCID,Puntel Robson L.¹²³^ORCID

Affiliation:

1. Universidade Federal do Pampa – Campus Uruguaiana, Programa de Pós-Graduação em Bioquímica (PPGBioq)

2. Uruguaiana

3. Brazil

4. Universidade Federal de Santa Maria – Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas (CCNE)

5. Santa Maria

6. Universidade Federal de Santa Maria – Departamento de Fisiologia e Farmacologia, Centro de Ciências da Saúde (CCS)

7. King's College London, Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience

8. London

9. UK

Abstract

Thimerosal (THIM) is a well-established antifungal and antiseptic agent widely used as a preservative in vaccines.

Funder

Medical Research Council

Biotechnology and Biological Sciences Research Council

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Financiadora de Estudos e Projetos

Instituto Nacional de Ciência e Tecnologia para Excitotoxicidade e Neuroproteção

Universidade Federal de Santa Maria

Universidade Federal do Pampa

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MT/C8MT00268A

Reference82 articles.

1. Chemical Speciation of Selenium and Mercury as Determinant of Their Neurotoxicity

2. A brain proteome profile in rats exposed to methylmercury or thimerosal (ethylmercury)

3. Milestone Achievement and Neurodevelopment of Rural Amazonian Toddlers (12 to 24 Months) with Different Methylmercury and Ethylmercury Exposure

4. Metals, oxidative stress and neurodegeneration: A focus on iron, manganese and mercury

5. Methylmercury-Induced Neurotoxicity: Focus on Pro-oxidative Events and Related Consequences

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