Lysine methyltransferase inhibitors: where we are now-Reference-Cited by-同舟云学术

Lysine methyltransferase inhibitors: where we are now

Published:2022 Issue: Volume: Page:
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Feoli Alessandra¹,Viviano Monica¹,Cipriano Alessandra¹,Milite Ciro¹,Castellano Sabrina¹,Sbardella Gianluca¹^ORCID

Affiliation:

1. Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno, via Giovanni Paolo II 132, I-84084 Fisciano, SA, Italy

Abstract

An updated outlook on protein lysine methyltransferase-disclosed modulators is presented, reporting their potency, mechanism of action and eventual use in clinical and preclinical studies.

Funder

Regione Campania

Università degli Studi di Salerno

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CB/D1CB00196E

Reference322 articles.

1. The Occurrence of iε-N-Methyl Lysine in Histones

2. Regulation of Transcription by a Protein Methyltransferase

3. Regulation of chromatin structure by site-specific histone H3 methyltransferases

4. Critical roles of non-histone protein lysine methylation in human tumorigenesis

5. Clinicopathologic significance of protein lysine methyltransferases in cancer

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