A controllable perfusion microfluidic chip for facilitating the development of retinal ganglion cells in human retinal organoids-Reference-Cited by-同舟云学术

A controllable perfusion microfluidic chip for facilitating the development of retinal ganglion cells in human retinal organoids

Published:2023 Issue:17 Volume:23 Page:3820-3836
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Gong Jing¹²³,Gong Yu²³,Zou Ting²³,Zeng Yuxiao²³,Yang Cao²³,Mo Lingyue²³,Kang Jiahui²³,Fan Xiaotang⁴,Xu Haiwei²³^ORCID,Yang Jun¹^ORCID

Affiliation:

1. Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, 400044, China

2. Southwest Hospital/Southwest Eye Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China

3. Key Lab of Visual Damage and Regeneration & Restoration of Chongqing, Chongqing, 400038, China

4. Department of Military Cognitive Psychology, School of Psychology, Third Military Medical University (Army Medical University), Chongqing, 40038, China

Abstract

A controllable perfusion microfluidic chip with the advantages of precisely controlling fluidic shear stress and oxygen concentration distribution is designed to promote the development of retinal organoids.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00054K

Reference71 articles.

1. Engineering three-dimensional microenvironments towards in vitro disease models of the central nervous system

2. Vascularized human cortical organoids (vOrganoids) model cortical development in vivo