Folding DNA into origami nanostructures enhances resistance to ionizing radiation-Reference-Cited by-同舟云学术

Folding DNA into origami nanostructures enhances resistance to ionizing radiation

Published:2021 Issue: Volume: Page:
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Sala Leo¹²³^ORCID,Zerolová Agnes¹²³⁴⁵,Rodriguez Alvaro¹²³^ORCID,Reimitz Dan¹²³,Davídková Marie⁶⁷⁸³^ORCID,Ebel Kenny⁹¹⁰¹¹¹²^ORCID,Bald Ilko⁹¹⁰¹¹¹²^ORCID,Kočišek Jaroslav¹²³^ORCID

Affiliation:

1. J. Heyrovský Institute of Physical Chemistry of the CAS

2. 18223 Prague

3. Czech Republic

4. Department of Chemistry

5. Technical University of Liberec

6. Department of Radiation Dosimetry

7. Nuclear Physics Institute of the CAS

8. 180 00 Prague

9. Institute of Chemistry-Physical Chemistry

10. Universität Potsdam

11. D-14476 Potsdam

12. Germany

Abstract

The multi-row design of DNA origami structures holds their shape even after severe nicking due to ionizing radiation and their folded structure has a protective effect, i.e., reduced damage compared to free scaffold and similarly sized plasmid DNA.

Funder

H2020 European Research Council

Grantová Agentura České Republiky

Deutscher Akademischer Austauschdienst

Akademie Věd České Republiky

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D1NR02013G