Complementary in vitro and in vivo strategies to assess the biological effects of the nano enabled food additives E171 and E551

Author:

Peropadre Ana12ORCID,Vega-Cuesta Patricia3ORCID,Fernández Freire Paloma2ORCID,Pulido Diego3ORCID,Carriere Marie1ORCID,de Celis Jose F.3ORCID

Affiliation:

1. CEA, CNRS, IRIG, SyMMES, CIBEST, Univ. Grenoble-Alpes, 38000 Grenoble, France

2. Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, Spain

3. Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Nicolás Cabrera 1, Madrid 28049, Spain

Abstract

Exposure to non-cytotoxic concentrations of E551 and E172 causes similar changes in the expression levels of genes related to the regulation of oxidative stress and DNA integrity in Drosophila intestines and human differentiated Caco-2 cells.

Funder

LabEx SERENADE

Secretaría de Estado de Investigación, Desarrollo e Innovación

Universidad Autónoma de Madrid

Publisher

Royal Society of Chemistry (RSC)

Subject

General Environmental Science,Materials Science (miscellaneous)

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