Artificial enzymes bringing together computational design and directed evolution

Author:

Mariz Beatriz de Pina12345,Carvalho Sara12345ORCID,Batalha Iris L.678910ORCID,Pina Ana Sofia12345ORCID

Affiliation:

1. UCIBIO

2. Chemistry Department

3. School of Science and Technology

4. NOVA University of Lisbon

5. 2829-516 Caparica

6. Nanoscience Centre

7. Department of Engineering

8. University of Cambridge

9. Cambridge

10. UK

Abstract

This manuscript reviews the combination of computational enzyme design and directed evolution and its advantages in the development of artificial enzymes.

Funder

Royal Society of Chemistry

Applied Molecular Biosciences Unit

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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