A ratiometric lysosomal pH probe based on the naphthalimide–rhodamine system
Author:
Affiliation:
1. Institute of Organic Chemistry
2. School of Chemistry and Chemical Engineering
3. Shandong University
4. Jinan 250100
5. P. R. China
6. Institute of Developmental Biology
7. School of Life Science
Abstract
The ratiometric pH probe RNL was constructed by integrating the naphthalimide moiety as an FRET donor into the rhodamine moiety as an FRET acceptor. The probe with a pKa of 4.82 could detect pH in the range of 4.50–5.50, selectively stain lysosome and detect lysosomal pH changes.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2015/TB/C4TB02082K
Reference56 articles.
1. Intracellular Alkalinization Suppresses Lovastatin-induced Apoptosis in HL-60 Cells through the Inactivation of a pH-dependent Endonuclease
2. Apoptosis induced in Jurkat cells by several agents is preceded by intracellular acidification.
3. Extracellular pH Is Required for Rapid Release of Insulin from Zn−Insulin Precipitates in β-Cell Secretory Vesicles during Exocytosis
4. Optical Nanosensors for Chemical Analysis inside Single Living Cells. 2. Sensors for pH and Calcium and the Intracellular Application of PEBBLE Sensors
5. Synthetic Macrocyclic Peptidomimetics as Tunable pH Probes for the Fluorescence Imaging of Acidic Organelles in Live Cells
Cited by 123 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Construction of a pH- and viscosity-switchable near-infrared fluorescent probe and its imaging application;Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy;2024-10
2. Ultrasensitive Dual Fluorophore-Conjugated Carbon Dots for Intracellular pH Sensing in 3D Tumor Models;ACS Applied Materials & Interfaces;2024-08-31
3. Organic fluorophores-based molecular probes with dual-fluorescence ratiometric responses to in-vitro/in-vivo pH for biosensing, bioimaging and biotherapeutics applications;Talanta;2024-08
4. Dual-emitting fluorescence ratiometric nanoprobes of in-vitro/in-vivo pH from constructions to sensing, imaging and therapeutic applications;Journal of Photochemistry and Photobiology C: Photochemistry Reviews;2024-03
5. Design and Application of Fluorescent Probes to Detect Cellular Physical Microenvironments;Chemical Reviews;2024-02-14
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3